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> Publications > Addictology - journal > Issues > 2003 / 2
15.03.2006
Drugs of abuse sensitization theory
The study presented brings a summarized view to the behavioral sensitization phenomenon frequently referred coherently with drug dependence. There are circumscribed both sensitization and tolerance which used to be often associated with drug dependence. Furthermore, terminological notes concerning to sensitization are explained and its neurobiological basis is outlined, especially pharmacodynamic changes which can underlie sensitization. Particularly, attention is focused on the changes of dopaminergic neurotransmitter system plasticity.
Key words: behavioral sensitization — drug dependence — dopamine
Authors: Jana Nováková, Alexandra Šulcová
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